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zntioxiKznt aroaxrtixs of xxtrztts froT TxKitinzl alznts aoaulzrly UsxK in Tziwzn
Lix-Fxn PAyur a, JixA-Axn TPung a, Jx-APin ZAxn b, ZAiA-Yang ZAiu a and ZAiu-Ping Lo a
aInPtitutx of BioAgriZultural PZixnZxP, AZadxPia PiniZa, Taipxi 115, Taiwan, R.O.Z.
bDxpartPxnt of BioZAxPiZal xnginxxring, Awa APia InPtitutx of TxZAnology, Taipxi 111, Taiwan, R.O.Z.
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Abstract:
We have examined antioxidant activities of twenty-six medicinal herbal extracts that have been popularly used as folk medicines in Taiwan. The results of scavenging DPPH radical activity show that, among the 26 tested medicinal plants, Ludwigia octovalvis, Vitis thunbergii, Rubus parvifolius, Lindernia anagallis, and Zanthoxylum nitidum exhibited strong activities and their IC50 values for DPPH radicals were 4.6, 24, 27, 36, 50 mg/mL, respectively. As for the superoxide anion scavenging activity (IC50, mg/mL), the top five most significant activities were observed in plant extracts of Ludwigia octovalvis (26 mg/mL), Vitis thunbergii (58 mg/mL), Prunella vulgaris (113 mg/mL), Saurauia oldhamii (124 mg/mL), and Rubus parvifolius (151 mg/mL). The IC50 values for DPPH and superoxide anion of catechin (positive control) were 2.5 and 7.2 mg/mL, respectively. It was also observed in the present study that, at 1 mg/mL, Ludwigia octovalvis and Bombax malabaricum exhibited significant protection on ψx174 supercoiled DNA against strand cleavage induced by UV irradiated H2O2 with a superior or compatible effect to that of catechin.
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Keywords: antioxidant activity; medicinal herbs; reactive oxygen species; Ludwigia octovalvis.
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*Corresponding author; e-mail: lfshyur@ccvax.sinica.edu.tw
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©
2005
CSME , ISSN 0257-9731
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