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CSME 2019/10
Volume 40 No.5
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539-546
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A Computational Study of Curvature Effect on the Coronary Diagnostic Parameters in Stenosed Coronary Artery
Irfan Anjum Badruddin a, Sarfaraz Kamangar a, Ali Algahtani a, M. Anas Khan b, Salman Ahmed N.J. c, C. A. Saleel a and T.M. Yunus Khan a
aDepartment of Mechanical Engineering, College of Engineering, King Khalid University, PO Box 394, Abha 61421, Kingdom of Saudi Arabia
bDepartment of Mechanical Engineering, Jamia Millia Islamia, Delhi, 110025 India
cDepartment of Mechanical and Industrial Engineering, Sultan Qaboos University, 33, Al-Khoud, Muscat 123, Oman.
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Abstract:
The presence of downstream curvature can affect the blood flow in artery leading to complicated hemodynamics. Thus, the current study is focused to explore the effect of downstream curvature of artery wall on the severity of stenosis by assessing the Fractional Flow Reserve, Lesion Flow Coefficient and Pressure Drop Coefficient under various downstream curvature angles in coronary artery. Computational fluid dynamics (CFD) of hyperemic flow in curved arteries was performed with various downstream curvature angles (00 300 600 900 and 1200) subjected to three different blockage (70%, 80% and 90%) area stenosis (AS). It is discovered that flow resistance caused by stenosis increases further due to the downstream curvature of artery. The FFR decreased by 5.4%, 8.6% and 13.1% for 70%, 80%, and 90%AS respectively as the downstream curvature of artery increased from 00 to 1200. The increase in CDP and decrease in LFC was found as the downstream curvature increased from 00 to 1200. The differences in diagnostic parameters FFR, CDP and LFC shows that misinterpretation could be possible while evaluating the functional significance of stenosis, so the downstream curvature must be contemplated while evaluating the importance of stenosis as an additional parameter for FFR.
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Keywords: Coronary artery, Stenosis, non-Newtonian, FFR.
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©
2019
CSME , ISSN 0257-9731
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